Some really good takes from a lot of people. I think we can all agree that there is an important distinction between what GW could and would do. My Lizardmen used to Aztec dinosaur people living in pseudo-South America; then they were half-remembered energy angels, summoned by space-faring Slann atop flying pyramids; and now they are sort of half-and-half. Words are words and text is cheap. Beasts of Chaos absolutely could be reimagined to fit a completely different role within the universe. Actually, they're not even evil goatfolk - they're just really hairy people living in the woods! And as for lore discrepancies? Retcon is a thing. "This is what we believed at the time, but now we actually know that..." and so on.
Now, does that mean that GW would make Beasts of Chaos part of Destruction? Personally, I don't believe that, not even for a minute. I wholeheartedly agree that the goats need a new, stronger, and more flavorful personality - one that ties them closer to the Mortal Realms. But I happen to think that the same is true of Seraphon, Skaven, Cities of Sigmar, and every other model range that hasn't seen much action since Age of Sigmar launched. I'm impressed with how the writers and community has embraced old concepts in a new story context, but I suppose the curse of sticking around for so long (like many others) is that I remember seeing those Ogres, Plague Monks, Cold One Riders, etc, on square bases! I think Daughters of Khaine are perhaps the golden standard in terms of keeping some old models and core themes, while adapting the army to a new world? I want to see more of that - I'm sure we all do.
Finally, how much of this speculation would have never taken form if they hadn't made Kragnos into a centaur? Why'd they go and make him a centaur? Why not just a super-big giant to slot in nicely with the Sons of Behemat - and every other army in Destruction? Could have been the guy still smashed dragon eggs and had to be put down long time ago. I think that part will always be weird to me...