I haven't gotten a chance to try him myself but I've been wanting to run Karios as well. Big reason because I "just as planned" myself years ago when they first released because I thought he was a cool model that would let me dabble in DoT and give me a fun caster to ally. Turns out it was a good choice.
From the very limited experience I've gotten with the new book (only 2 games for Forbidden Power at 1.5k points) the Epitome along with our heroes can be enough if spells are an edge to your game plan and not a big part. I think Karios while really powerful needs to have a plan for him to be worth the points. Something like using gateway to help nuke screens, having better chance at slothful stupor being successfully cast, or even for endless spells.
I was running invaders with sybarites and rod of misuse in both those games; with the GHB2019 I didn't need the spells as much because I had so many command points I could burn for re-roll ones to hit and save rolls that mystic shield and acquiescence weren't as important. I think he's a really fun powerful addition for us but far from a necessary must include.